Optimal Timing and Approaches for First Tangential Excision in Patients with ≥70% TBSA Burns: Insights from a Retrospective Cohort of a Mass Casualty Incident.

Objective: We aim to determine the optimal timing and approaches for first tangential excision of severely burned patients ≥70% total body surface area (TBSA).

Background: Early tangential excision is the gold-standard surgical therapy for full-thickness burns. However, there are debates about its optimal timing and approaches for severely burned patients ≥70%TBSA.

Boosting Amino Acid Synthesis with WO Sub-Nanoclusters.

The conversion of nitrate-rich wastewater and biomass-derived blocks into high-value products using renewably generated electricity is a promising approach to modulate the artificial carbon and nitrogen cycle. Here, a new synthetic strategy of WO sub-nanoclusters is reported and supported on carbon materials as novel efficient electrocatalysts for nitrate reduction and its coupling with α-keto acids. In acidic solutions, the NH-NHOH selectivity can also optimized by adjusting the potential, with the total FE exceeding 80% over a wide potential range.

Microporous carbon derived from waste plastics for efficient adsorption of tetracycline: Adsorption mechanism and application potentials.

In recent years, the accumulation of waste plastics and emergence plastic-derived pollutants such as microplastics have driven significantly the development and updating of waste plastic utilization technology. This study prepared the porous carbon (PC-1-KOH) material directly from polyethylene terephthalate (PET) in waste plastic bottles using KOH activation and molten salt strategy for efficient removal of antibiotic tetracycline (TC). The maximum removal efficiency of TC was 100.

Bioelectronic and photogenerated electron synergistic catalyzed removal of chlorhexidine: Degradation and mechanism.

The extensive use of the antimicrobial compound chlorhexidine (CHD) has emerged as a significant threat to both the ecological environment and human health. To address this concern, a photo-electrochemical cell-microbial fuel cell (PMFC) system was studied for CHD removal by incorporating, for the first time, the photocatalysts black phosphorus/carbon nitride (BPCN) and CuO into the bioanode and air cathode of an MFC, respectively. By combining electrochemical, macro-genomic, and intermediate product analyses, the underlying mechanisms of bioelectronic and photoelectronic synergies were elucidated.

Suppressing the progression of bladder cancer using cyclovirobuxine D based on network pharmacology and bioinformatics approaches.

Limited treatment options are available for bladder cancer (BCa) resulting in extremely high mortality rates. Cyclovirobuxine D (CVB-D), a naturally alkaloid, reportedly exhibits notable antitumor activity against diverse tumor types. However, its impact on CVB-D on BCa and its precise molecular targets remain unexplored.