Publications by authors named "G Wills"

A large body of research investigates the determinants of stunting in young children, but few studies have considered which factors are the most important predictors of stunting. We examined the relative importance of predictors of height-for-age z-scores (HAZ) and stunting among children under 5 years of age in seven of the most food-insecure districts in South Africa using data from the Grow Great Community Stunting Survey of 2022. We used dominance analysis and variable importance measures from conditional random forest models to assess the relative importance of predictors.

View Article and Find Full Text PDF
Article Synopsis
  • Enoxaparin, a medication used to treat blood clots, is dosed based on actual body weight, but its effectiveness can vary in obese patients due to distribution differences related to body composition.
  • The study evaluated dosing strategies and monitored Antifactor Xa (AFXa) levels in obese patients receiving enoxaparin, reviewing data from 762 patients over a year.
  • Results showed no significant link between dosing and AFXa levels, and the rates of treatment failure (2.2%) and bleeding (5%) were comparable to general expectations, indicating that obesity did not independently impact treatment outcomes.
View Article and Find Full Text PDF

Background: Large language models (LLMs) can assist providers in drafting responses to patient inquiries. We examined a prompt engineering strategy to draft responses for providers in the electronic health record. The aim was to evaluate the change in usability after prompt engineering.

View Article and Find Full Text PDF

Background:  Existing monitoring of machine-learning-based clinical decision support (ML-CDS) is focused predominantly on the ML outputs and accuracy thereof. Improving patient care requires not only accurate algorithms but also systems of care that enable the output of these algorithms to drive specific actions by care teams, necessitating expanding their monitoring.

Objectives:  In this case report, we describe the creation of a dashboard that allows the intervention development team and operational stakeholders to govern and identify potential issues that may require corrective action by bridging the monitoring gap between model outputs and patient outcomes.

View Article and Find Full Text PDF

Background: The clinical narrative in electronic health records (EHRs) carries valuable information for predictive analytics; however, its free-text form is difficult to mine and analyze for clinical decision support (CDS). Large-scale clinical natural language processing (NLP) pipelines have focused on data warehouse applications for retrospective research efforts. There remains a paucity of evidence for implementing NLP pipelines at the bedside for health care delivery.

View Article and Find Full Text PDF