Publications by authors named "G Williamson"

With large wildfires becoming more frequent, we must rapidly learn how megafires impact biodiversity to prioritize mitigation and improve policy. A key challenge is to discover how interactions among fire-regime components, drought and land tenure shape wildfire impacts. The globally unprecedented 2019-2020 Australian megafires burnt more than 10 million hectares, prompting major investment in biodiversity monitoring.

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A key strategy to mitigate postprandial hyperglycemia involves inhibiting α-amylases, which commence the starch digestion process in the gut. This study examined the inhibitory effects of resveratrol and stilbenoid tetramers, vaticanol B, (-)-hopeaphenol, and vatalbinoside A on human salivary and pancreatic α-amylases experimentally and through molecular docking studies. Vaticanol B demonstrated the most potent inhibition with IC values of 5.

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Introduction: Post-traumatic stress disorder (PTSD) and comorbid cannabis use disorder (CUD) is a growing concern amongst UK veterans. Co-occurrence of problematic cannabis use, and PTSD is associated with greater PTSD symptom severity, decreased likelihood of cannabis use cessation, worse clinical outcomes, and increased societal burden. Despite increased screening efforts among veterans, there are no effective strategies for predicting risk for PTSD and problematic drug use escalation before these conditions develop, worsen, or become chronic.

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Article Synopsis
  • Free or conjugated aromatic/phenolic acids originate from various sources, including diet, metabolism of certain neurotransmitters, pharmaceuticals, and gut microbiota processing of dietary compounds.
  • Research has compiled data on 112 aromatic/phenolic acids in human biological samples and found that around 30% of studies show bioactivity at low concentrations (≤1 μmol/L), particularly benefiting vascular tissues.
  • Some important metabolites, like phenyl-lactic and phenyl-propanoic acids, have been largely overlooked, indicating a need for further research to explore their potential health benefits and biological activities.
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