Publications by authors named "G Wegner"
Background And Study Objective: Delirium is an organic mental syndrome significantly associated with long-term cognitive decline, increased hospital stays and higher mortality. This systematic review of randomised controlled trials (RCTs) with meta-analysis assesses the association of remimazolam with postoperative cognitive function and delirium compared with non-benzodiazepine hypnotics.
Design: Systematic review of RCTs with meta-analysis.
Neonatal hyperbilirubinemia is a prevalent condition, with a risk of serious complications. Phototherapy is the standard treatment for significant cases, but its limitations highlight the need for additional options. Zinc sulfate has emerged as a potential adjunctive treatment.
View Article and Find Full Text PDFArticle Synopsis
- Emergence agitation, a common issue after nasal surgeries, can lead to increased restlessness and injury, with younger patients and certain medical factors heightening its risk.* -
- A network meta-analysis was conducted following rigorous guidelines, reviewing randomized controlled trials on both drug and non-drug methods to prevent this agitation, utilizing multiple scientific databases for data collection.* -
- The analysis included 17 studies with over 2,100 patients, identifying effective treatments such as dexmedetomidine, nerve blocks, ketamine, and pre-anesthesia nasal compression, suggesting a range of options for clinicians to enhance postoperative care.*
Introduction: The potential benefit of intraoperative wound irrigation (IOWI) in preventing surgical site infection (SSI) remains unclear. The use of antimicrobial agents (AMA) or antiseptic agents (ASA) is controversial worldwide.
Methods: We performed a systematic review and meta-analysis of randomized clinical trials comparing AMA or ASA with saline solution in patients who underwent abdominal surgery.
Article Synopsis
- Remimazolam is a new anesthetic agent developed to replace propofol, which has notable hemodynamic effects that may pose risks during surgery.
- A systematic review of 16 clinical trials involving 1951 patients assessed the hemodynamic impacts of remimazolam compared to propofol, revealing that remimazolam leads to lower instances of intraoperative hypotension, bradycardia, and reduced need for vasoactive drugs.
- The findings suggest that remimazolam has a safer and more favorable side effect profile than propofol during general anesthesia, making it a promising alternative.