Publications by authors named "G Walter Locatelli"

Background: To perform self-care, individuals with a chronic illness must be able to perceive bodily changes (ie., interoception) so they can respond to symptoms when they arise. Interoception is regulated by the insular cortex of the brain.

View Article and Find Full Text PDF

Background: Collaboration between nurses is crucial in improving quality in healthcare and plays a key role in increasing nurses' job satisfaction.

Objectives: Our study aimed to investigate the level of collaboration between nurses working in Turkey and Italy and its related factors. The study also deepened the point of view of clinical nurses and nurse managers on this topic.

View Article and Find Full Text PDF

Accumulation of immune cells and proteins in the subarachnoid space (SAS) is found during multiple sclerosis and in the animal model experimental autoimmune encephalomyelitis (EAE). Whether the flow of cerebrospinal fluid (CSF) along the SAS of the spinal cord is impacted is yet unknown. Combining intravital near-infrared (NIR) imaging with histopathological analyses, we observed a significantly impaired bulk flow of CSF tracers within the SAS of the spinal cord prior to EAE onset, which persisted until peak stage and was only partially recovered during chronic disease.

View Article and Find Full Text PDF

Background: In Italy, Diagnosis-Related Groups (DRGs) have been adopted for hospital services reimbursement. In some Italian regions, nurse staffing allocation is purely volume-based, with different minutes/patient/day categories determined by the type of hospital ward. The Information System of Nursing Performance (SIPI) is a valid and reliable tool assessing nursing care complexity as an indicator of the actual nursing care demand.

View Article and Find Full Text PDF
Article Synopsis
  • - Multiple sclerosis (MS) is an autoimmune disease causing inflammation and damage in the central nervous system, leading to symptoms like muscle dysfunction that can affect mobility and quality of life.
  • - Current treatments mainly focus on neuroinflammation, leaving a need for therapies targeting muscle function, as many people with MS experience skeletal muscle issues that can precede mobility-related disabilities.
  • - Exercise, particularly aerobic and resistance training, is highlighted as an effective intervention to improve muscle strength, reduce fatigue, and enhance overall well-being in individuals with MS, emphasizing the importance of implementing these exercises early on.
View Article and Find Full Text PDF