Publications by authors named "G Waisman"

Article Synopsis
  • A novel cardiovascular risk (CVR) calculator has been developed that includes Lipoprotein(a) [Lp(a)] levels to provide a more accurate assessment of cardiovascular risk.
  • In a study of 671 patients, high Lp(a) levels were found in 22.7% of the cases, leading to a significant increase in lifetime and 10-year CVR for two-thirds of the participants.
  • Reducing low-density lipoprotein cholesterol (LDL-C) or systolic blood pressure (SBP) effectively compensated for the increased risk associated with Lp(a) levels in a large proportion of patients.
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Background: After the acute infection, COVID-19 can produce cardiac complications as well as long-COVID persistent symptoms. Although vaccination against COVID-19 represented a clear reduction in both mortality and ICU admissions, there is very little information on whether this was accompanied by a decrease in the prevalence of post-COVID cardiac complications. The aim of this study was to analyze the relationship between COVID-19 vaccination and the prevalence of post-COVID cardiac injury assessed by echocardiogram, and long-COVID persistent cardiac symptoms.

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Objective: In this analysis of the telehealth-based Vascular health ASsessment Of The hypertENSive patients Registry, we checked how 24-h central and peripheral hemodynamics compare with hypertension-mediated organ damage (HMOD).

Methods: In 646 hypertensive patients (mean age 52 ± 16 years, 54% males, 65% treated) we obtained ambulatory brachial and central SBP and pulse pressure (PP), SBP, and PP variability, pulse wave velocity and augmentation index with a validated cuff-based technology. HMOD was defined by an increased left ventricular mass index (cardiac damage, evaluated in 482 patients), an increased intima-media thickness (vascular damage, n = 368), or a decreased estimated glomerular filtration rate or increased urine albumin excretion (renal damage, n = 388).

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The VASOTENS Registry is an international telehealth-based repository of 24-hour ambulatory blood pressure monitorings (ABPM) obtained through an oscillometric upper-arm BP monitor allowing combined estimation of some vascular biomarkers. The present paper reports the results obtained in 1200 participants according to different categories of CV risk. Individual readings were averaged for each recording and 24-hour mean of brachial and aortic systolic (SBP) and diastolic blood pressure (DBP), pulse wave velocity (PWV), and augmentation index (AIx) obtained.

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Background: Mean platelet volume (MPV) is a risk factor for cardiovascular and inflammatory diseases.

Aim: To evaluate the association between high MPV and 90-day mortality after an episode of venous thromboembolism (VTE).

Material And Methods: Retrospective cohort of 594 patients with a median age of 73 years (58% women) with a first episode VTE, included in an institutional Thromboembolic Disease registry between 2014 and 2015.

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