Publications by authors named "G W Nash"
Background: The watch-and-wait strategy provides an opportunity to pursue non-operative management in rectal cancer patients with clinical complete response after neoadjuvant therapy. The management of those with near complete response remains controversial.
Objective: We assessed the oncologic outcomes of patients managed by watch-and-wait versus total mesorectal excision according to clinical response to neoadjuvant therapy.
Article Synopsis
- Hemipelvectomy is a complex surgery typically aimed at curing cancer, but its use for palliative care in advanced cancer cases is quite rare and not well understood.
- A retrospective study reviewed outcomes for 10 patients with stage IV cancer who underwent this palliative procedure, revealing significant complications and limited survival benefits.
- While some patients experienced reduced pain, none showed functional improvement post-surgery, indicating that more conservative treatment options should be considered, especially for patients with less severe pelvic tumors.
Background: Appendiceal epithelial tumors are rare and encompass a broad set of adenocarcinoma histologies, including mucinous (mAC), colonic-type (cAC), and goblet cell (GCA) adenocarcinomas. It has previously been reported that nodal disease predicted recurrence in patients with nonmetastatic appendiceal adenocarcinomas, supporting diagnostic laparoscopy with right hemicolectomy for staging and assessment for risk of recurrence. In this update, we sought to identify predictors of nodal disease on initial diagnostic pathology in nonmetastatic adenocarcinomas.
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