The Clinical Course of Minimal Change Nephrotic Syndrome With Onset in Adulthood or Late Adolescence: A Case Series.

Background: Few studies have examined the treatment and outcome of adult-onset minimal change nephrotic syndrome (MCNS). We retrospectively studied 125 patients who had MCNS with onset in either adulthood or late adolescence. Presenting characteristics, duration of initial treatment and response to treatment, relapse patterns, complications, and long-term outcome were studied.

Ticagrelor-induced renal failure leading to statin-induced rhabdomyolysis.

Renal function deterioration is a rather frequent side effect of ticagrelor; this is especially so in patients over the age of 75, with pre-existent mild renal failure and/or taking an angiotensin receptor inhibitor. We describe a patient in whom deterioration of renal function due to ticagrelor led to a rise in serum concentration of rosuvastatin which resulted in rhabdomyolysis. The presented case emphasises the importance to check renal function routinely before and one month after starting ticagrelor and to screen carefully for possible interactions with other drugs.

[A woman with ongoing anaemia].

In a 65-year-old female with iron deficiency anaemia, video capsule endoscopy showed an ulcerative polyp in the proximal ileum. After histological examination we made the diagnosis 'granuloma pyogenicum', a rare cause of gastrointestinal bleeding. After partial resection of the small intestine, the anaemia was cured.

[Liver cirrhosis due to hepatitis E in a kidney transplant patient].

Until recently, hepatitis E was considered to be an infectious disease that resolved without any long-term complications. We describe a 47-year-old woman who presented with a decompensated liver cirrhosis with ascites and peripheral oedema, 14 years after successful kidney transplantation. A previous extensive analysis of persistent liver enzyme disorders had not yielded a diagnosis, whereas now laboratory tests showed slightly abnormal liver results.