Publications by authors named "G Vishwanath"
Background Burn injuries pose a significant global public health challenge, causing substantial morbidity and mortality, particularly in low- and middle-income countries. Timely and effective wound coverage is critical in treating severe burns to prevent infection, reduce pain, and promote healing. Cadaveric skin grafts (allografts) have become essential in treating extensive burn wounds, serving as temporary biological dressings to prepare the wound bed for autografting.
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- Giant basal cell carcinoma (GBCC) is a rare and aggressive type of skin cancer, exemplified by a case study of a man in his 60s with a large ulcer on his heel that had persisted for a year.
- The patient underwent surgeries including biopsies and an excision with a skin graft to treat the aggressive lesion.
- The study highlights the relationship between tumor size and behavior, as well as factors like tumor location, surgical margins, and potential for recurrence or spread.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), continues to cause substantial morbidity and mortality in the ongoing global pandemic. Understanding the fundamental mechanisms that govern innate immune and inflammatory responses during SARS-CoV-2 infection is critical for developing effective therapeutic strategies. Whereas interferon (IFN)-based therapies are generally expected to be beneficial during viral infection, clinical trials in COVID-19 have shown limited efficacy and potential detrimental effects of IFN treatment during SARS-CoV-2 infection.
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