Buprenorphine-naloxone versus buprenorphine for opioid use disorder during pregnancy: A systematic review and meta-analysis.

Background: The standard of care for treating opioid use disorder (OUD) during pregnancy includes either buprenorphine or methadone. Although buprenorphine-naloxone presents an alternative due to the reduced risk of misuse , evidence regarding its impact on pregnancy and infant health remains limited. This systematic review and meta-analysis aims to compare buprenorphine-naloxone vs buprenorphine alone for OUD during pregnancy, assessing gestational and neonatal outcomes.

Short-Term Safety and Effectiveness for Tenecteplase and Alteplase in Acute Ischemic Stroke.

Importance: Tenecteplase is an alternative to alteplase for emergency treatment of acute ischemic stroke. However, limited data are available comparing their clinical effectiveness in routine clinical practice.

Objective: To compare short-term effectiveness and safety outcomes for patients with ischemic stroke treated with intravenous tenecteplase vs alteplase.

Detection of Cassava Mosaic Geminiviruses Using Loop-Mediated Isothermal Amplification (LAMP).

A real-time loop-mediated isothermal amplification (LAMP) is described to diagnose cassava mosaic disease (CMD). The disease continues to cause great damage in Sub-Saharan African countries threatening food security. Early detection of the pathogen is paramount to control the spread of the disease and promote the safe exchange of clean planting material.

Cellular and extracellular matrix aspects of the nasal cartilage in the fetus and early infant.

A comprehensive description of nasal septal cartilage (NSC) across all age groups is an unmet need. This information could help improve facial reconstruction, particularly in childhood. We describe cellular distribution and metabolic activity in the NSC of fetus, newborn, and 2-year-old infants using postmortem samples.

Genomic and morphological features of an Amazonian Bacillus thuringiensis with mosquito larvicidal activity.

The occurrence of mosquito-borne diseases is increasing, and their geographical range is expanding due to climate change. New control measures are urgently needed to combat these debilitating and, in some cases, fatal diseases. Bacteria of the genus Bacillus are of interest due to the production of bioactive compounds, including those useful for insect control.