[Medication assisted activation of unveoscleral outflow of intraocular fluid in glaucoma: pathogenic aspects].

The article provides an overview of the main groups of IOP-lowering drugs which activate uveoscleral outflow in glaucoma and this activation is a key component of mechanism of action of these drugs. The issues related to the change of tone of ciliary muscle and its participation in uveoscleral outflow, and also relationship of accommodation and aqueous flow in glaucoma pathogenesis and possible pharmacological effects of these processes are being discussed.

[Treatment of depressive conditions with S-methylmethionine (vitamin U)].

Results of treating depressive states (manic-depressive psychosis, involutional and vascular depressions) with S-methylmethionine (vitamin "U") are presented. The vitamin was found to produce a marked antidepressant effect in depressive states of various nosology irrespectively of the duration of the depression phase or preceding treatment. The authors suggest that studies of the effect of the vitamin and its clinical use as an antidepressant should be continued.