Structure, properties, and decomposition in biological systems of a new nitrosyl iron complex with 2-methoxythiophenolyls, promising for the treatment of cardiovascular diseases.

A new promising binuclear tetranitrosyl iron complex with 2-methoxythiophenolyl of the composition [Fe(CHOS)(NO)] (complex 1), which acts on the therapeutic targets of cardiovascular diseases, guanylate and adenylate cyclase, has been synthesized. X-ray diffraction data show the presence of two isoforms of complex 1; according to quantum chemical calculations, the structure of only the trans isomer is stable in solutions. The processes of transformation of complex 1 in DMSO, in aqueous solutions, as well as in the presence of bovine serum albumin, reduced glutathione, and mucin were studied.

Enhancing Photostability of Complex Lead Halides through Modification with Antibacterial Drug Octenidine.

The high power-conversion efficiencies of hybrid perovskite solar cells encourage many researchers. However, their limited photostability represents a serious obstacle to the commercialization of this promising technology. Herein, we present an efficient method for improving the intrinsic photostability of a series of commonly used perovskite material formulations such as MAPbI, FAPbI, CsFAPbI, and CsMAFAPbI through modification with octenidine dihydroiodide (), which is a widely used antibacterial drug with two substituted pyridyl groups and two cationic centers in its molecular framework.

Synthesis and Properties of Ethylene/propylene and Ethylene/propylene/5-ethylidene-2-norbornene Copolymers Obtained on -Et(2-MeInd)ZrMe/Isobutylaluminium Aryloxide Catalytic Systems.

Ethylene/propylene (E/P) and ethylene/propylene/5-ethylidene-2-norbornene (E/P/ENB) copolymers were obtained on -Et(2-MeInd)ZrMe activated by a number of isobutylaluminium aryloxides: (2,6-BuPhO-)AlBu (1-DTBP) (2,6-Bu,4-Me-PhO-)AlBu (1-BHT), (2,4,6-BuPhO-)AlBu (1-TTBP), (2,6-Bu,4-Me-PhO-)AlBu (2-BHT), (2,6-BuPhO-)2AlBu (2-DTBP), [(2-Me,6-Bu-CHO)AlBu] (1-MTBP), [(2,6-Ph-PhO)AlBu] (1-DPP). This study shows how the structure of an activator influences catalytic activity and polymer properties, such as the copolymer composition, molecular weight characteristics, and thermophysical and mechanical properties. It has been shown that both the introduction of a bulky substituent in the para-position of the aryloxy group and the additional aryloxy group in the structure of an activator lead to a significant decrease in activity of the catalytic system in all studied copolymerization processes.

Exploring the Limits: Degradation Behavior of Lead Halide Perovskite Films under Exposure to Ultrahigh Doses of γ Rays of Up to 10 MGy.

Herein, we show that thin films of MAPbI, FAPbI, (CsMA)PbI, and (CsMAFA)PbI, where MA and FA are methylammonium and formamidinium cations, respectively, tolerate ultrahigh doses of γ rays approaching 10 MGy without significant changes in their absorption spectra. However, among the studied materials, FAPbI was the only one that did not form metallic lead due to its extreme radiation hardness. Infrared near-field optical microscopy revealed the radiation-induced depletion of organic cations from the grains of MAPbI and their accumulation at the grain boundaries, whereas FAPbI on the contrary lost FA cations from the grain boundaries.

Solubility Enhancement of Dihydroquercetin via "Green" Phase Modification.

Dihydroquercetin (DHQ) is a promising antioxidant for medical applications. The poor water solubility of this flavanonol at ambient conditions inhibits its implementation in clinical practice as an injectable dosage form. Thus, increasing water solubility is a critical step toward solving this problem.