[Morphological study of placenta and liver of pregnant rats in experimental endotoxicosis and after ceolite protection].

In 45 rats and 120 fetuses the protective effect of food, containing the additives of natural ceolites, on the outcome of pregnancy complicated by an acute experimental endotoxicosis, caused by hyperthermic challenge of the animals, was studied. Using gravimetric, histological, histochemical, electron microscopical methods and monitoring the markers of endogenous intoxication, it was demonstrated that the consumption of ceolite additives contributed to the increase of resistance of the organism to the extremal challenge. Ceolite enteroprotection of acute endotoxicosis, caused by hyperthermic challenge of the pregnant rats, resulted in the increased survival of animals, lower embryonic losses, adaptive changes in placenta and maternal liver.

[Morpho-functional characteristic of kidneys in mother, fetus and the offspring subjected to vibration of industrial frequency during gestation].

The aims of the present study were to investigate the nature of morpho-functional changes in the kidneys in mother, fetus and the offspring subjected to the dosed effect of vibration during gestation. The study was performed in pregnant female Wistar rats (n = 28), fetuses (n = 26) and the offspring aged 3 months (n = 20). Rats were subjected to vibration from Day 9 to Day 19 of gestation (the period of intensive metanephros development), using vibration test bench with fixed parameters: frequency of 32 Hz and acceleration of 50 m/s2.

[The receptor-mediated endocytosis of complexes of colloidal gold with high-density lipoproteins by the sinusoidal cells of the isolated rat liver].

Rat hepatic sinusoidal cells absorption of native high-density lipoproteins was studied by electron microscope. Visualization of the endocytosis process was achieved by binding of lipoprotein particles and colloidal gold. The study was carried out on isolated liver perfusing by oxygenated nutritional media which consist of colloidal gold-lipoproteins conjugates.

[Endocytosis by liver cells during stimulation of the mononuclear phagocyte system by yeast polysaccharides].

Endocytosis (phagocytosis, fluid-phase- and receptor-mediated endocytosis) by liver cells, lysosomal enzyme activities have been studied during macrophages stimulation by yeast polysaccharides. It was shown that like macrophages stimulator zymosan, yeast polysaccharides cryelan and rhodexman increased the carbon particles phagocytosis. The most effective was intravenous administration of yeast polysaccharides.