[A comparative study of the reactions of the peripheral blood neutrophils from donors and from lymphogranulomatosis patients to arachidonate stimulation of the cells].

Arachidonate-induced aggregation and generalization of active oxygen forms (OAF) by peripheral blood neutrophils in donors were studied in donors and Hodgkin's disease patients. Leukocytes of the latter had incomplete ability to produce AOF in response to cell stimulation with arachidonic acid. The study of arachidonate-induced aggregation of neutrophils indicated no differences in the speed of the process in the patients and donors.

[The distribution of HLA-system antigens in lung cancer patients].

Data on 152 cases of lung cancer were studied in an attempt to identify relationship between immunogenetic markers of the HLA system, on the one hand, and histologic pattern of the disease and effectiveness of radiation treatment, on the other. Control group included 200 healthy blood donors. Eight A locus antigens and 16 B locus antigens were studied.

[20 years of experience in using high-energy electron accelerators].

The authors summed up their 20-year experience in the clinical use of a linear accelerator of electrons and a Siemens betatron (42 MeV) in the Research Institute of Oncology and Radiology, Ministry of Health of the Byelorussian SSR. Comparative advantages and shortcomings of both accelerators and the results of their technical modifications were considered. A section in the paper, devoted to the clinical aspects of tumor therapy, is concerned with the description of a number of methods of irradiation with various types of therapeutic beams, energies, field sizes, directions, various regimens of dose fractionation in time and irradiated volume.

[A decrease in the efficiency of radiation damage repair in HeLa tumor cells with their preliminary irradiation at low radiation doses (0.1 Gr)].

In experiments with tumor HeLa cells, a study was made of the survival rate of both the whole population and individual clonogenic cells after irradiation within different regimes at a cumulative dose of 4 Gy. The results obtained prompt a conclusion that the preirradiation with a dose of 0.1 Gy decreases the efficiency of repair of radiation-induced damages to cells.