[Tolerance of functional and exercise tests during 1-year antiorthostatic hypokinesia].

During 370 days 9 healthy young volunteers were exposed to antiorthostatic hypokinesia. Group A consisting of 4 subjects performed exercises similar to those regularly made by Mir crewmembers and Group B consisting of 5 subjects did not exercise for 120 days and then performed experimental exercise regimens. It was demonstrated that the health status of men long exposed to head-down tilting can be controlled with the aid of various countermeasures.

[Effect of a 30-day period of hypokinesia on various physiologic and biochemical indicators during maximal physical load].

Exercise tolerance of test subjects who remained bed rested (Group A) and who exercised while being supine (Group B) was measured before and after 30-day head-down tilt (-8 degrees). Special attention was given to the parameters that characterize energy supply of working muscles. The data obtained after 30-day bed rest did not reveal any changes in the Group B subjects and showed the following changes in the Group A subjects: maximum oxygen consumption decreased by 10.

[Functional status of the human cardiorespiratory system after 30 hours' antiorthostatic hypokinesia].

Before and after 30-day head-down tilt (-8 degrees) the cardiorespiratory function of six healthy volunteers was assessed using an exercise test (aerobic workload on the treadmill that grew to the maximal level). After hypokinesia the maximal oxygen consumption decreased by 9.9% and total oxygen debt by 23% (P less than 0.

[Effect of motor activity on aerobic performance of healthy subjects].

Bicycle ergometry studies in which 120 healthy male volunteers, aged 20--40, look part, showed that aerobic performance depended on their normal motor activity. In the test subjects, leading an active mode of life, maximum oxygen uptake and general work capacity were significantly higher than in those leading a sedentary mode of life. The data obtained give evidence that the people with diminished muscle activity should be recommended to do regular exercises in order to maintain aerobic performance.

[Some physiological effects caused by 30 days of bed rest in different body positions].

Eighteen male test subjects were exposed to a 30-day bed rest with the foot end of the bed tilted at +6 degrees, -2 degrees or -6 degrees. Control subjects were allowed a normal mode of life during the same period of time. Hypokinesia was shown to play the leading role in the genesis of most changes, since control subjects displayed no changes.