Transgeneration effects of N-stearoylethanolamine in irradiated rats.

Objective: to explore possible transgeneration effects in the rats offspring of the first generation of parents subject ed to the combined effects of N stearoylethanolamine (NSE) and external exposure.Materials and metods. In the first generation rats of both sexes born to parents who have experienced the combined influence of ionizing radiation at a dose of 2.

Potential use of N-stearoylethanolamine in radiation medicine.

A new class of biologically active compounds N-acylethanolamines with properties of endogenous cannabinoids are considered in the terms of promising use in radiation medicine both in the acute phase for the prevention and treatment of ionizing radiation damage and in remote period for the treatment of the effects of exposure.

Peculiarity of changes of peripheral blood hematological indices in rats under N-stearoilethanolamine administration conditioned by combined effects of ionizing radiation and stress.

Unlabelled: Objective - to investigate the peculiarities of peripheral blood indices changes in rats under the N-stearoiletanolamine treatment before and after combined effects of ionizing radiation and stress.

Methods: hematological, statistical.

Results: Per oral administration of NSE (10,0 mg / kg) before and after the combined effects of single whole-body irradiation (6.

Combined effect of N-stearoyiletanolamine and ionizing radiation on hematological indices of peripheral blood in rats.

Unlabelled: The study objective was to explore the peculiarities of peripheral blood values in rats under the combined influence of 10.0 mg/kg N-stearoylethanolamine (NSE) and 6.0 Gy dose of ionizing radiation to identify the radiomodifying properties of the drug.

Experimental study of radiomodifying properties of N-stearoilethanolamine under a combined impact of ionizing radiation and stress.

Objective: to investigate the radiomodifying properties of N-stearoilethanolamine (NSE) in experiment under different conditions of a combined impact of ionizing radiation and stress.

Methods: biochemical, statistical.

Results: The radiomodifying properties of N-stearoilethanolamine were revealed under different conditions of a combined impact of ionizing radiation and stress according to the indices of plasma concentrations of TBA-active products, nitrite-anions and catalase activity.