Application of the genetic risk model for the analysis of predisposition to nonlacunar ischemic stroke.

The purpose of our study was to analyze the predictive ability of the multiplicative model of genetic risk of nonlacunar ischemic stroke (IS) for independent samples from Russia. A total of 181 patients and 360 healthy controls were included in this study. The discriminative accuracy of model was evaluated by the area under the receiver operating characteristic curve (AUC).

[The specific features of the hemostatic system and platelet metabolism in pregnant women with gestosis for the prediction of the clinical status of neonatal infants].

The specific features of the hemostatic system and platelet metabolism were studied in women, who were 32-38 weeks pregnant and had varying gestosis, in relation to the clinical status of neonatal infants. The pregnant women who had higher levels of fibrinogen and soluble fibrin-monomer complexes along with decreased platelet enzyme activity regard their neonates' status as having Apgar scores of 6 or less and requiring additional medical intervention.

[An analysis of using the graphic monitoring of ventilation for an optimal choice of respiratory management parameters in patients with acute respiratory distress syndrome].

The potentialities of graphic ventilation monitoring (graphic monitor "Servo Screen 390", Siemens Elema, Sweden) were analyzed for optimizing the respiratory management parameters in 48 obstetric and gynecology patients with acute respiratory distress syndrome (ARDS). The ventilation loops and curves, ALV parameters, mechanical lung properties, gas blood composition and gas indices were dynamically evaluated during examination stages. The graphic ventilation monitoring, when used for respiratory management in patients with ARDS, provides for optimizing, in the real time mode, the PEEP and Vt levels, which is in line with the AVL "safety" concept.

[Diagnostics and correction of thrombohemorrhagic impairments in patients with purulent-septic complications in obstetrics and gynecology].

The clinical course of thrombohemorrhagic complications was studied in 56 patients, aged 18 to 38, with sepsis, which developed due to obstetric and gynecologic processes on days 1, 3, 5, 7 and 10 after surgery. The patients were treated, 1999-2003, at the obstetric intensive-care and consultation center, MUZA Maternity Hospital No. 1, Krasnoyarsk.