Publications by authors named "G V Chaitanya"
Stereoelectroencephalography (SEEG) has emerged as a transformative tool in epilepsy surgery, shedding light on the complex network dynamics involved in focal epilepsy. This review explores the role of SEEG in elucidating the role of deep brain structures, namely the basal ganglia and thalamus, in epilepsy. SEEG advances understanding of their contribution to seizure generation, propagation, and control by permitting precise and minimally invasive sampling of these brain regions.
View Article and Find Full Text PDFA 32-year-old right-handed woman presented with medically and surgically refractory left temporal neocortical epilepsy secondary to focal cortical dysplasia who underwent stereoelectroencephalography involving the centromedian nucleus of the thalamus. With the use of real-time stereoelectroencephalography monitoring, four electroclinical seizures were aborted by administering high-frequency stimulation at the centromedian nucleus at seizure onset. Seizures before stimulation were all associated with ictal apnea, while those with stimulation had no ictal apnea.
View Article and Find Full Text PDFArticle Synopsis
- Sleep disturbances and drug-resistant seizures are major issues for those with idiopathic generalized epilepsy (IGE), and thalamic deep brain stimulation (DBS) could be a potential treatment.
- A study combining wearable sleep monitoring and EEG showed that high-frequency stimulation (125 Hz) worsened sleep and increased seizures, while low-frequency stimulation (10 Hz) improved both sleep quality and seizure control.
- The findings emphasize the importance of customizing DBS settings to individual patients' sleep needs to enhance treatment effectiveness and quality of life for those with refractory epilepsy.
Article Synopsis
- The study aimed to investigate the occurrence of cardiac arrhythmias during generalized convulsive seizures (GCSs) and their potential link to sudden unexpected death in epilepsy (SUDEP).
- Researchers monitored adult epilepsy patients using video-EEG and various cardiological assessments to identify different types of arrhythmias occurring during seizures.
- The findings could provide insights into the relationship between seizure severity markers and cardiac arrhythmias, contributing to understanding the risk factors associated with SUDEP.