Changes in kidney function and oxidative stress biomarkers in offspring from dams treated with dexamethasone during lactation in Wistar rats.

Background: The effects of maternal exposure to glucocorticoids during gestation on various organs in the offspring have been reported in literature. There is paucity of information on the effects of maternal glucocorticoids treatment during lactation on organ functions in the offspring. The present study was designed to investigate the changes in kidney function and oxidative stress biomarkers in offspring of dams treated with dexamethasone during lactation in Wistar rats METHODS: Twenty pregnant rats (180-200g) were divided into 4 groups (n=5).