Publications by authors named "G Urrutia"
Article Synopsis
- The study focuses on the importance of core strength for stroke recovery and examines whether adding Core Stability Exercises (CSE) to conventional physiotherapy (CP) enhances recovery outcomes.
- Eighty-seven early stroke survivors were divided into two groups: one receiving CSE alongside CP and the other receiving only CP, with assessments conducted before and after a 5-week intervention.
- Results showed that the experimental group experienced significant improvements in dynamic sitting balance, trunk coordination, lower limb spasticity, and overall balance compared to the control group, suggesting that incorporating CSE may be beneficial for stroke rehabilitation.
Article Synopsis
- Harmful algal blooms (HABs), especially those from toxin-producing microalgae like Prorocentrum micans, are a recurring issue in Patagonian fjords, and a significant HB-HAB occurred in Northwest Chilean Patagonia during February-March 2022.
- Observations showed a dramatic increase in P. micans cell density from low levels in January to a peak of over 8.3 x 10 cells/mL by mid-February, associated with warmer sea temperatures and varying salinity.
- Satellite images and oceanographic modeling revealed that water currents and temperature variations in the Gulf of Ancud supported the development and maintenance of this harmful algal bloom, indicating a hotspot for both HABs and HB-HAB
Almost 50% of patients with myelodysplastic syndrome (MDS) are refractory to first-line hypomethylating agents (HMAs), which presents a significant clinical challenge considering the lack of options for salvage. Past work revealed that immune checkpoint molecules on peripheral myeloblasts and immune cells are up-regulated after HMA treatment. Therefore, we conducted a Phase I/II clinical trial combining guadecitabine (an HMA) and atezolizumab (an immune checkpoint inhibitor) to treat HMA-relapsed or refractory (HMA-R/R) MDS patients.
View Article and Find Full Text PDFBackground: Pragmatic randomized controlled trials are getting more interest to improve trials' external validity. This study aimed to assess how pragmatic the design of the self-labelled pragmatic randomised controlled trials in the manual therapy field is.
Methods: We searched MEDLINE and the Cochrane Central Register of Controlled Trials for self-labelled pragmatic randomised controlled trials in the manual therapy field until January 2024 were included.
Purpose: This scoping review aims to deepen the understanding of end-of-life anticancer drug use in lung cancer patients, a disease marked by high mortality and symptom burden. Insight into unique end-of-life treatment patterns is crucial for improving the appropriateness of cancer care for these patients.
Methods: Comprehensive searches were carried out in Medline and Embase to find articles on the utilization of anticancer drugs in the end of life of lung cancer patients.