Primary Modified Predescemetic Deep Anterior Lamellar Keratoplasty in Acute Corneal Hydrops.

Purpose: To report primary treatment of acute corneal hydrops (CH) with a modified technique of predescemetic deep anterior lamellar keratoplasty (pdDALK).

Methods: This prospective interventional case series included 9 eyes with acute CH that underwent pdDALK as primary treatment. Technique modifications included a bevel-up needle, creating tissue emphysema as a guide for dissection, using small aliquots of air directed away from break, manual deeper dissection using a blunt dissector, centripetal dissection leaving the area of Descemet membrane (DM) break for last, retention of minimal stroma above DM tear, and tamponade of DM tear with air in the anterior chamber.

Dissolution studies on tablets of ibuprofen using chitosan.

An attempt has been made to study the release retardant behaviour of chitosan in ibuprofen tablets. Three different ibuprofen tablets were prepared by using 1,3 and 5% chitosan paste. In vitro evaluations were carried out by using dissolution testing apparatus U.