Publications by authors named "G Troncone"
Article Synopsis
- Giacomo Torno was born in Naples in 1539 or 1541 and became a member of the Clerics Regular Theatines at 18, being welcomed on October 30, 1558.
- He suffered a stroke on December 4, 1608, and experienced torment during his illness, characterized by spasms and discomfort, leading to his death 45 days later.
- Analysis of his mummified body revealed a skin discontinuity at the sacrum, suggesting a wound that occurred during his life, which has been linked to the first recorded instance of the Kennedy terminal ulcer.
Introduction: Personalized medicine has revolutionized the clinical management of patients with solid tumors. However, the large volumes of molecular data derived from next-generation sequencing (NGS) and the lack of harmonized bioinformatics pipelines drastically impact the clinical management of patients with solid tumors. A possible solution to streamline the molecular interpretation and reporting of NGS data would be to adopt automated data analysis software.
View Article and Find Full Text PDFIn elderly patients with high-risk classic Hodgkin lymphoma (c-HL), we evaluated the impact of a new modality treatment without bleomycin, that is, liposomal doxorubicin (NPLD)-based regimen plus consolidation radiotherapy of residual nodal masses (RNMs), on overall survival (OS) and progression free survival (PFS). In this retrospective study (2013-2023) conducted in tertiary hospitals in the bay of Naples (Italy), 50 older adults (median age, 69 years; range, 60-89) with advanced stage c-HL received frontline treatment with MVD ± irradiation. MVD consisted of 25 mg/m of NPLD along with standard Vinblastine and Dacarbazine for a total of 6 cycles (twelve iv administrations, every 2 weeks) followed by radiation of RNMs with size ≥ 2.
View Article and Find Full Text PDFIntroduction: Identifying mutations in the epidermal growth factor receptor (EGFR) gene is crucial for individualized treatment of non-small cell lung cancer (NSCLC) patients. Accordingly, several methodologies and instruments are now commercially available to detect these alterations. The aim of this study was to examine the performance of next generation sequencing (NGS) in detecting both common and uncommon EGFR gene mutations in advanced NSCLC patients.
View Article and Find Full Text PDFArticle Synopsis
- Fine needle cytology (FNC) is an important method for differentiating between benign and malignant lymph node conditions due to its low invasiveness, affordability, and high accuracy.
- Proper management of the samples collected during the procedure is crucial for achieving the best diagnostic results, particularly through careful examination of the cellular structures.
- The text discusses a specific pattern called 'concentric ovals distribution,' often seen in benign lymph nodes, which can help cytopathologists accurately diagnose reactive hyperplasia.