Publications by authors named "G Teg Pipes"
Female genital mutilation and cutting: a survey of child abuse pediatricians.
BMC Womens Health
June 2024
Background: As global immigration from countries with a high prevalence of female genital mutilation and cutting (FGM/C) has grown in the United States (US), there is need for pediatricians to have adequate training to care for these patients. The objective of this study is to determine the level of knowledge and attitudes of child abuse pediatricians (CAPs) towards FGM/C in the US.
Methods: This cross-sectional study distributed a peer-reviewed survey to US CAPs-members of the Helfer Society-to assess their attitudes, knowledge, clinical practice, and education about FGM/C.
Postpartum stroke trends, risk factors, and associated adverse outcomes.
Am J Obstet Gynecol MFM
May 2023
Article Synopsis
- Management of postpartum stroke has seen quality improvement efforts, but there's a lack of recent national data on readmissions.
- This study used the Nationwide Readmissions Database from 2013 to 2019 to analyze trends, risk factors, and complications related to postpartum stroke readmissions within 60 days after discharge.
- Results showed that out of over 21 million deliveries, 5,006 had stroke readmissions, with no significant change in overall readmission rates, while risk factors like preeclampsia were linked to higher odds of readmission.
Treatment with thymosin beta 4 (Tβ4) reduces infarct volume and preserves cardiac function in preclinical models of cardiac ischemic injury. These effects stem in part from decreased infarct size, but additional benefits are likely due to specific antifibrotic and proangiogenic activities. Injected or transgenic Tβ4 increase blood vessel growth in large and small animal models, consistent with Tβ4 converting hibernating myocardium to an actively contractile state following ischemia.
View Article and Find Full Text PDFArticle Synopsis
- Thymosin beta 4 (Tβ4) benefits chronic myocardial ischemia through two action phases—an acute antiapoptotic/anti-inflammatory phase and a chronic progenitor cell activation phase.
- In a rat model, the study tested short-term (3-day) and long-term (3-day plus ongoing) Tβ4 treatments, finding that long-term treatment significantly reduced infarct size and improved hemodynamic performance.
- Both treatment regimens reduced plasma biomarkers of myocyte injury but did not lead to increased blood vessel density, indicating that repeated Tβ4 dosing might be necessary for noticeable cardiac functional improvements.