Publications by authors named "G Tedeschi"
Article Synopsis
- The Itel-MMSE is an easy-to-use telephone screening tool for dementia that gained traction during COVID-19 but needed validation and faced issues like a ceiling effect.
- This study standardized and validated the Itel-MMSE, recruiting 707 healthy participants and 368 individuals with Mild Cognitive Impairment and Alzheimer's Disease to establish new cut-off scores.
- Results indicated that the Itel-MMSE is effective in identifying dementia, with strong performance metrics in distinguishing between normal conditions and cognitive impairments, supporting its use in remote screenings.
Article Synopsis
- Macrophages can behave in two main ways when activated: inflammatory (M1) or anti-inflammatory (M2), and tracking these behaviors is important for understanding immune function.
- Current methods for monitoring macrophage polarization are either static or not suitable for complex environments, so the researchers developed a new approach using genetically engineered luciferase reporters.
- Their method allows for long-term observation of macrophage types in both 2D and 3D formats with high resolution, paving the way for better monitoring of immune cells and other complex biological networks.
Transcranial magnetic stimulation (TMS) methods have become exciting techniques for altering brain activity and improving synaptic plasticity, earning recognition as valuable non-medicine treatments for a wide range of neurological disorders. Among these methods, repetitive TMS (rTMS) and theta-burst stimulation (TBS) show significant promise in improving outcomes for adults with complex neurological and neurodegenerative conditions, such as Alzheimer's disease, stroke, Parkinson's disease, etc. However, optimizing their effects remains a challenge due to variability in how patients respond and a limited understanding of how these techniques interact with crucial neurotransmitter systems.
View Article and Find Full Text PDFReduced neurovascular coupling of the visual network in migraine patients with aura as revealed with arterial spin labeling MRI: is there a demand-supply mismatch behind the scenes?
J Headache Pain
October 2024
Article Synopsis
- Research indicates that patients with migraine with aura exhibit increased activity in visual cortices but struggle with adequate vascular supply during triggers, which may lead to aura symptoms.
- A study involving MRI assessed cerebral blood flow and connectivity in patients with migraine with and without aura, along with healthy controls.
- Results showed heightened blood flow in the visual cortex of migraine with aura patients, along with decreased neurovascular coupling, suggesting a misalignment between energy demand and supply in the brain.
Background: Dairy cow milking practices require cleaning and disinfection of the teat skin before and after milking to ensure the safety and quality of milk and prevent intramammary infections. Antimicrobial proteins of natural origin can be valuable alternatives to traditional disinfectants. In a recent field trial, we demonstrated that a teat dip based on a nisin A-producing Lactococcus cremoris (L) had comparable efficacy to conventional iodophor dip (C) in preventing dairy cow mastitis.
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