Publications by authors named "G Tantari"
Background: Insulin resistance in children and adolescents with obesity is linked to increased risk of type 2 diabetes mellitus and cardiovascular disease. The SPISE index, based on values of fasting triglycerides (mg/dL), HDL cholesterol (mg/dL), and BMI (kg/m2), shows promise in predicting insulin resistance in children.
Methods: This study aimed to identify a SPISE cut-off for detecting insulin resistance and evaluate its relationship with pubertal development, anthropometrics, and glycometabolic profile in 232 children and adolescents, 105 males and 127 females (median age 13.
Article Synopsis
- The study investigates foreign body ingestion (FBI) in children under 18 in Italy, highlighting the prevalence and trends from 2015 to 2020.
- A total of 5,771 cases were analyzed, with the majority occurring at home, mostly involving children under 6, and commonly featuring blunt objects.
- The results indicate stable rates of FBI over time, urging the importance of preventive strategies to protect young children, especially those 5 and under, from such incidents.
Article Synopsis
- The case report highlights the successful use of an Advanced Hybrid Closed Loop (AHCL) system for insulin treatment in a young patient with permanent neonatal diabetes mellitus (PNDM) due to a genetic condition.
- The patient transitioned from intravenous insulin to a Medtronic Minimed 780G insulin pump, and by age 2, automated insulin delivery significantly improved glycaemic control and met treatment goals.
- Over a one-month follow-up, there was a notable increase in Time in Range (TIR) and a reduction in hyperglycaemia, with no severe complications reported, emphasizing the importance of good glycaemic management for young patients' health and development.
Article Synopsis
- Cystic fibrosis related diabetes (CFRD) is linked to worse nutrition and lung function, with limited exploration of new treatment technologies like Advanced Hybrid Closed Loop (AHCL) systems.
- A study was conducted on 10 CFRD patients using AHCL, measuring HbA1c levels and glucose monitoring over 1 year, revealing significant improvements in glycemic control and insulin needs.
- While the study showed positive trends in time spent within healthy glucose levels, further research with a larger group is required to confirm these benefits and their impact on overall health in CF patients.
Background And Aims: Foreign body ingestion (FBI) in children requires early identification to prevent adverse outcomes and may necessitate endoscopic or surgical intervention. This study aims to develop a nomogram that identifies children who require urgent surgical or endoscopic intervention by using the patient's medical history and clinical parameters collected at admission.
Methods: This study is a retrospective review (01/2015-12/2020) of a multicenter case series of children admitted for FBI.