Publications by authors named "G Tambakis"

Background And Aims: Acute-on-chronic liver failure (ACLF) has a 22%-74% 28-day mortality rate and 30%-40% 30-day readmission rate. We investigated the acceptability and feasibility of a multimodal community intervention for ACLF.

Methods: A single-arm nonrandomized pilot study of consecutive participants with ACLF was conducted in a tertiary health service.

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Background: An episode of acute ulcerative colitis (UC) represents an important watershed moment in a patient's disease course.

Aims: To derive a personalised algorithm for identifying patients at high risk of corticosteroid non-response from variables available at hospital presentation using a large prospectively collected acute UC patient database and machine learning-based techniques.

Methods: We analysed data from 682 consecutive presentations of acute UC.

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Article Synopsis
  • - Foreign body ingestion is a frequent reason for Emergency Department visits, particularly in vulnerable groups such as the elderly, individuals with psychiatric issues, and prisoners, with a study in Melbourne analyzing data from 2017 to 2021 involving 63 patients.
  • - The study found that a significant portion (65%) of cases involved prisoners, with common ingested items being batteries (23%), drug-containing balloons (17%), and razor blades (16%); most ingestions were categorized as high-risk.
  • - Conservative management was successfully applied in 55% of cases without complications, although 31% of patients returned within 30 days, highlighting the ongoing challenges in managing those with high-risk, intentional ingestions and mental health concerns.
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Background: Acute-on-chronic liver failure (ACLF) represents a rising global healthcare burden, characterised by increasing prevalence among patients with decompensated cirrhosis who have a 28-day transplantation-free mortality of 33.9%. Due to disease complexity and a high prevalence of socio-economic disadvantage, there are deficits in quality of care and adherence to guideline-based treatment in this cohort.

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