Publications by authors named "G T Van Horn"

The medical community continues to regard organophosphate nerve agent poisoning as a significant concern. Due to the lack of therapeutic options for the nicotinic signs and symptoms for certain agents (e.g.

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Structural firefighters are exposed to an array of polycyclic aromatic hydrocarbons (PAHs) as a result of incomplete combustion of both synthetic and natural materials. PAHs are found in both the particulate and vapor phases in the firefighting environment and are significantly associated with acute and chronic diseases, including cancer. Using a fireground exposure simulator (FES) and standing mannequins dressed in four different firefighter personal protective equipment (PPE) conditions, each with varying levels of protective hood interface and particulate-blocking features, the efficacy of the hoods was assessed against the ingress of PAHs (specifically, naphthalene).

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Applying artificial intelligence (AI) to image-based morphological profiling cells offers significant potential for identifying disease states and drug responses in high-content imaging (HCI) screens. When differences between populations (e.g.

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Article Synopsis
  • - The study investigates the effectiveness of somatostatin analogues (SSA) in treating small, non-functioning pancreatic neuroendocrine tumors (PanNETs ≤2 cm) compared to active surveillance.
  • - Data was collected from 72 patients, showing that those treated with SSA had not yet reached median progression-free survival (PFS), whereas the surveillance group had an estimated PFS of 85 months with a 21.9% progression or death rate.
  • - The findings suggest that SSA significantly delays tumor progression and spread in patients with these small PanNETs, highlighting its potential as an effective treatment strategy.
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