Publications by authors named "G T Sudarshan"

Article Synopsis
  • Complex Regional Pain Syndrome (CRPS) is a rare and difficult-to-treat neuropathic disorder affecting less than 200,000 people in the U.S. each year, with current treatments mainly providing inadequate pain relief.
  • This systematic review aimed to evaluate the effectiveness of low-dose naltrexone in treating various chronic pain syndromes through an extensive search of medical literature, resulting in the analysis of 30 relevant studies.
  • Findings suggest that low-dose naltrexone may offer symptom relief for chronic pain, dystonia, and sleep issues, but further focused studies are necessary to confirm its efficacy specifically for CRPS.
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Article Synopsis
  • Chronic axial spinal pain, primarily caused by facet joints, leads to significant disability and increased healthcare costs, emphasizing the need for effective diagnostic and therapeutic interventions.
  • The study focuses on evidence-based methods for diagnosing and treating facet joint issues, utilizing literature reviews and established standards to guide recommendations.
  • Key findings highlight that physical examinations are essential for diagnosis, while fluoroscopic or CT guidance is strongly recommended for interventions, with varying levels of evidence backing different diagnostic techniques.*
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The flowers of flax (linseed) are blue-hued, ephemeral and self-pollinating, and the seeds are typically brown. A century-old interest in natural yellow seed variants and a historical model point to recessive alleles in B1, D and G loci being responsible, but the functional aspects had remained unknown. Here, we characterized the "D" locus by quantitative trait loci (QTL) mapping and identified a FLAVONOID 3'5' HYDROXYLASE (F3'5'H) gene therein.

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