The influence of COVID-19 on temporo-mandibular disorders.

Temporomandibular disorders are multi-factorial conditions affected by psychological, biomechanical, and neuromuscular factors. Stress and anxiety experienced during the pandemic are capable of influencing and aggravating temporomandibular disorders and orofacial pain. The study aimed to analyze whether the coronavirus infection can directly affect these diseases.

Mesenchymal stem cell transplantation attenuates growth of chemotherapy treated oral squamous cell carcinoma in an animal model.

Background: Recent studies have demonstrated mesenchymal stem cell migration toward tumor locations. When applied locally, MSCs interact with the locally residing host cells. The mechanisms behind this are still unclear.

Use of the universal pain assessment tool for evaluating pain associated with temporomandibular disorders in youngsters.

Aim: Determine, whether the UPAT could be used as an extra tool to collect data on functional TMJ pain and to assess orofacial pain levels related to temporomandibular disorder(s) (TMD) in youngsters.

Methods: Patients were screened at the N1 Dental Clinic of Tbilisi State Medical University. The clinical scores of possible functional jaw pain were collected using the UPAT, to indicate pain severity on a visual scale during different jaw movements (opening, closing and lateral).

NEW METHOD OF BONE AUGMENTATION DU-RING DENTAL IMPLANTATION IN LAB ANIMALS.

The success of surgical treatment of maxillo-facial bone defects depends on bone regeneration ability. Bone volume can be restored by surgical implantation of various biomaterials, which have ability either to accomplish mechanically the function of bone or to produce the induction effect on bone regeneration process. Latest advancements in tissue engineering are enabling to find new materials with significantly less disadvantages than the currently used osteoplastic materials.

GUIDED REGENERATION OF JAW BONE DEFECTS WITH COMBINATION OF OSTEOPLASTIC MATERIALS AND STEM CELLS.

Reconstruction of mandibular defects is a challenging issue in maxillofacial surgery. Success of the treatment is defined by the process of reparative regeneration of bone tissue, which is often accompanied with wound infection, failure of microcirculation and tissue hypoxia. Aim of our project was to demonstrate the advantage of osteoplastic material and bone marrow derived mesenchymal stem cells combination in regeneration of lower jaw bone defect.