Publications by authors named "G Sukanya"
Diffuse Hypopigmented Keratoses: An Under-Reported and Often Misdiagnosed Entity.
Indian Dermatol Online J
December 2022
Article Synopsis
- Diffuse hypopigmented keratotic lesions are associated with various skin conditions such as pityriasis versicolor, stucco keratoses, and Darier's disease, each with unique clinical and histological features.
- A new type of lesion called disseminated hypopigmented keratoses (DHK) is considered when diagnosing these conditions.
- Bedside tests like potassium hydroxide wet mount and dermatoscopy are crucial for accurately diagnosing these lesions, which are typically benign and not related to any systemic issues.
Screening for the 3'UTR Polymorphism of the PXR Gene in South Indian Breast Cancer Patients and its Potential Role in Pharmacogenomics.
Sundaramoorthy Revathidevi Ravi Sudesh Varadharajan Vaishnavi Muthukrishnan Kaliyanasundaram Kilyara George MaryHelen Ganesan Sukanya
Asian Pac J Cancer Prev
February 2017
Background: Breast cancer, the commonest cancer among women in the world, ranks top in India with an incidence rate of 1,45,000 new cases and mortality rate of 70,000 women every year. Chemotherapy outcome for breast cancer is hampered due to poor response and irreversible dose-dependent cardiotoxicity which is determined by genetic variations in drug metabolizing enzymes and transporters. Pregnane X receptor (PXR), a member of the nuclear receptor superfamily, induces expression of drug metabolizing enzymes (DMEs) and transporters leading to regulation of xenobiotic metabolism.
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