Publications by authors named "G Subbiahdoss"

Mucin, proteoglycan, glyconectin, and hyaluronan intermolecular binding in the physiological hydrated state forms the native glycocalyx ultrastructure via the polyvalent interactions of their similar bottle-brush morphologies. This ultrastructure provides a variety of essential cellular recognition/adhesion and selective filtration functions. Unfortunately, for decades, the glycocalyx architecture was only examined in the non-native dehydrated/fixed state.

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Biomaterial-associated infections pose severe challenges in modern medicine. Previously, we reported that polyanionic DNA surface coatings repel bacterial adhesion and support osteoblast-like cell attachment in monoculture experiments, candidate for orthopaedic implant coatings. However, monocultures lack the influence of bacteria or bacterial toxins on osteoblast-like cell adhesion to biomaterial surfaces.

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The administration of exogenous hormones emerged as an essential tool for field studies in endocrinology. However, working with wild animals remains challenging, because under field conditions not every available method meets the necessary requirements. Achieving a sustained elevation in hormone levels, while simultaneously minimising handling time and invasiveness of the procedure is a difficult task in field endocrinology.

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Bacteria forming biofilms at oil-water interfaces have diverse metabolism, they use hydrocarbons as a carbon and energy source. Kombucha is a fermented drink obtained from a complex symbiotic culture of bacteria and yeast, where acetic acid bacteria present in kombucha use sugars as a carbon source to produce cellulosic biofilms. We hypothesize that in kombucha can adsorb to and use hydrocarbons as the sole energy source to produce cellulosic biofilms.

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The ability of bacteria to adhere to and form biofilms on implant surfaces is the primary cause of implant failure. Implant-associated infections are difficult to treat, as the biofilm mode of growth protects microorganisms from the host's immune response and antibiotics. Therefore, modifications of implant surfaces that can prevent or delay bacterial adhesion and biofilm formation are highly desired.

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