Publications by authors named "G Strauss"

Background And Hypothesis: In accordance with the Cognitive Model of Negative Symptoms, defeatist performance beliefs (DPBs) are an important psychosocial mechanism of negative symptoms in schizophrenia-spectrum groups. DPBs are also mediators of negative symptom improvement in clinical trials. Despite the clinical significance of DPBs and their inclusion as a mechanism of change measure in clinical trials, the psychometric properties of the DPB scale have not been examined in any schizophrenia-spectrum group.

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Background And Hypotheses: The lack of psychometrically validated assessment tools designed specifically to assess negative symptoms in individuals at clinical high risk (CHR) for psychosis represents a significant barrier to the early identification and prevention of psychosis. To address this need, the Negative Symptom Inventory-Psychosis Risk (NSI-PR) was developed based on the iterative, data-driven approach recommended by the National Institute of Mental Health consensus conference on negative symptoms.

Study Design: This manuscript reports the results of the second study phase that psychometrically validates the final 11-item version of the scale in data collected across 3 sites.

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Background: A recent environmental systems theory of negative symptoms in schizophrenia (SZ) proposes a role for reductions in social networks that exist within microsystems (i.e., the contexts in which social interactions occur).

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Article Synopsis
  • Sepsis is a serious condition that poses risks to human health and has significant economic implications; recent research highlights various factors, including cellular senescence, that contribute to this issue.
  • In an experimental study on male mice, sepsis was induced via cecal ligation and puncture, leading to noticeable pulmonary damage and increased markers associated with acute lung injury and cellular senescence.
  • The results revealed complex changes in senescence-related pathways, suggesting that while some markers decrease, others may increase during the early stages, pointing to the need for further research on the long-term impacts of sepsis on multiple organ systems.
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Speech Sound Disorders (SSDs) are prevalent communication problems in children that pose significant barriers to academic success and social participation. Accurate diagnosis is key to mitigating life-long impacts. We are developing a novel software solution-the Speech Movement and Acoustic Analysis Tracking (SMAAT) system to facilitate rapid and objective assessment of motor speech control issues underlying SSD.

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