Cause of death based on systematic post-mortem studies in patients with positive SARS-CoV-2 tissue PCR during the COVID-19 pandemic.

Importance: Assessment of the causative association between the COVID-19 and cause of death has been hampered by limited availability of systematically performed autopsies. We aimed to present autopsy-confirmed causes of death in patients who died with COVID-19 and to assess the association between thrombosis and diffuse alveolar damage consistent with COVID-19 (DAD).

Methods: Consecutive forensic (n = 60) and clinical (n = 42) autopsies with positive post-mortem SARS-CoV-2 PCR in lungs (age 73 ± 14 years, 50% men) were included.

[The current course of Brill's disease].

The paper presents the data on the clinical course and laboratory diagnosis of Brill's disease in 30 patients. The absence of absolute and not infrequently basic and indicating signs of the disease as well as its frequent course in the presence of the concurrent diseases significantly hinder its clinical diagnosis, particularly at the initial stage of the disease. Unwanted clinical and epidemiological consequences could be avoided only in case of a constant medical alertness and understanding of specificity of the current course of Brill's disease as well as a provisional hospitalization within 5 days of all the patients with unclear diagnosis who have fever into the infectious department of a hospital.

[The differential diagnosis of acute intestinal infections].

The authors evaluate contemporary possibilities of clinico-epidemiological and laboratory diagnosis of intestinal yersiniosis in the clinical practice. Data are reported on infestation of the environment with yersiniosis pathogen in this territory and the clinical picture of gastrointestinal form of yersiniosis and its symptomatology that is of help in the diagnosis. Perfection of laboratory diagnosis is of great importance in this respect.

[Use of diuretics in the treatment of patients with viral hepatitis].

The effectiveness of intensification of diuresis by means of hypothiaside and furosemide has been studied during treatment of 135 patients with viral hepatitis A and B. Both these agents were found to posses the same effect which was manifested by lessening of the intoxication syndrome, total blood toxicity and convalescence terms. A therapeutic effect of diuretics is most pronounced in moderately severe form of the disease.