MjCyc: Rediscovering the pathway-genome landscape of the first sequenced archaeon, .

The genome of () DSM 2661 was the first Archaeal genome to be sequenced in 1996. Subsequent sequence-based annotation cycles led to its first metabolic reconstruction in 2005. Leveraging new experimental results and function assignments, we have now re-annotated creating an updated resource with novel information and testable predictions in a pathway-genome database available at BioCyc.