Cold-driven strategies as pre-fermentative techniques on winemaking: A review.

As a pre-fermentative practice, cold may facilitate the extraction of grape compounds, resulting in differentiated wines. To explore the potential of these practices, extensive research has been conducted on scientific publications since 2004. There are four main ways to apply cold in pre-fermentative practices: ice wine production, berry freezing, cold maceration of grape must, and cryoconcentration of grape must.

An electronic warning system helps reduce the time to diagnosis of sepsis.

Objective: To describe the improvements of an early warning system for the identification of septic patients on the time to diagnosis, antibiotic delivery, and mortality.

Methods: This was an observational cohort study that describes the successive improvements made over a period of 10 years using an early warning system to detect sepsis, including systematic active manual surveillance, electronic alerts via a telephonist, and alerts sent directly to the mobile devices of nurses. For all periods, after an alert was triggered, early treatment was instituted according to the institutional sepsis guidelines.

Comorbidities Might Condition the Recovery of Quality of Life in Survivors of Sepsis.

Purpose:: To assess how preexisting disabling comorbidities (DC) affect the recovery rate of quality of life (QOL) over time in sepsis survivors.

Methods:: A prospective study was conducted on sepsis survivors who answered the 36-Item Short Form Health Survey (SF-36) 7 days after discharge from the intensive care unit. Subsequent interviews were held at 3, 6, and 12 months.