Predictive Value of FDG Uptake on PET for Future Immune Checkpoint Inhibitor-Mediated Colitis: A Case Series.

: Immune-mediated colitis (IMC) is a common immune-related adverse event during immune checkpoint inhibitor (ICI) therapy. This case series and review aimed to highlight atypical cases of IMC and explore the potential of PET/CT to predict imminent ICI colitis. : Through a descriptive, retrospective study at a tertiary cancer center, we identified adult patients receiving ICIs for any cancer between 2010 and 2022 who also underwent PET/CT for routine cancer surveillance during this time.

Salience maps for judgments of frontal plane distance, centroids, numerosity, and letter identity inferred from substance-invariant processing.

A salience map is a topographic map that has inputs at each x,y location from many different feature maps and summarizes the combined salience of all those inputs as a real number, salience, which is represented in the map. Of the more than 1 million Google references to salience maps, nearly all use the map for computing the relative priority of visual image components for subsequent processing. We observe that salience processing is an instance of substance-invariant processing, analogous to household measuring cups, weight scales, and measuring tapes, all of which make single-number substance-invariant measurements.

Pneumatosis intestinalis in cancer patients who received immune checkpoint inhibitors.

Purpose: Immune checkpoint inhibitor (ICI) therapy may give rise to immune-related adverse events (irAEs). Pneumatosis intestinalis (PI), or gas within the bowel wall, has very rarely been observed following ICI therapy, and its clinical significance is unclear. We described the clinical characteristics and outcomes of PI as a possible irAE in cancer patients.

Investigating the Impact of Community Volunteerism on the Mental Health of Medical Students.

Objective: This study aimed to analyze the impact of community service on the mental health of medical students through their perception of stress.

Methods: The 10-item Perceived Stress Scale was used to measure the stress levels of 82 medical students over a 3-month period. Additional survey questions gauged students' weekly volunteer experiences in clinical and nonclinical settings and their perceived effects on stress and quality of life.

Sclerosing mesenteritis following immune checkpoint inhibitor therapy.

Purpose: Sclerosing mesenteritis (SM), a fibroinflammatory process of the mesentery, can rarely occur after immune checkpoint inhibitor (ICI) therapy; however, its clinical significance and optimal management are unclear. We aimed to assess the characteristics and disease course of patients who developed SM following ICI therapy at a single tertiary cancer center.

Methods: We retrospectively identified 12 eligible adult cancer patients between 05/2011 and 05/2022.