Publications by authors named "G Spadaro"

Acute suppurative thyroiditis (AST), a rare yet potentially life-threatening infection, comprises less than 1 % of neck pathologies and requires prompt treatment. Symptoms range from neck pain and fever to dysphagia and possible abscess formation. Broad-spectrum antibiotics are the primary treatment; however, surgical drainage may be necessary for abscesses to prevent systemic infection.

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Introduction: In patients with Hereditary Angioedema (HAE) related to primary C1 inhibitor deficiency (C1INH), the defective clearance of immune complexes and apoptotic materials along with impairment of normal humoral response potentially leads to autoimmunity. Few studies report evidence on autoimmune diseases in C1INH-HAE, but no large population studies focus on rare connective tissue diseases (RCTDs). We aim at evaluating for the first time prevalence and distribution of RCTDs - Systemic Lupus Erytematosus (SLE), primary Sjogren Syndrome (SjS), primary antiphospholipid syndrome (APS), Systemic Sclerosis (SSc), and mixed connective tissue diseases (MCTD) in a large Italian cohort of C1INH-HAE patients.

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Cooperation underlies the ability of groups to realize collective benefits (e.g., creation of public goods).

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Article Synopsis
  • - This study found two types of patients with severe eosinophilic asthma who respond differently to the medication mepolizumab.
  • - Patients with a family history of asthma, positive skin tests, and higher lung function showed better responses to treatment.
  • - The findings emphasize the importance of tailoring treatment plans to individual patient characteristics for improved outcomes.
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