Publications by authors named "G Sokolowski"
Article Synopsis
- - Amiodarone, a key antiarrhythmic drug, can lead to a severe side effect called amiodarone-induced thyrotoxicosis (AIT), which can result in life-threatening cardiac issues, prompting the need for urgent treatment options like thyroidectomy or radioactive iodine therapy.
- - A study analyzed the outcomes of 75 patients with severe AIT from 2014 to 2022, revealing that many suffered from critically low thyroid hormone levels and required urgent intervention due to worsening heart conditions.
- - Of the patients needing radical therapy, 6 died before treatment, 6 underwent thyroidectomy, and 8 were treated successfully with radioactive iodine, highlighting the complexities and challenges in managing AIT in conjunction with
Heme oxygenase-1 (HO-1, HMOX1) degrades heme protecting cells from heme-induced oxidative damage. Beyond its well-established cellular functions, heme has emerged as a stabilizer of G-quadruplexes. These secondary DNA structures interfere with DNA replication.
View Article and Find Full Text PDFArticle Synopsis
- * A study at a Polish hospital found that while only 1 case of MC was recorded from 2015 to 2019, there were 10 cases reported during and after the pandemic, highlighting a concerning trend.
- * Factors contributing to the increase included worsening hypothyroidism due to non-compliance with therapy, as well as difficulties in accessing required medication, emphasizing the need for better patient communication and ongoing primary care for those with thyroid issues.