Publications by authors named "G Sofianidis"

Article Synopsis
  • Ewing sarcoma is a serious cancer that mainly affects children and teens, with the EWSR1/FLI1 fusion gene being a common genetic factor, but it hasn’t been targeted for treatment or used to predict outcomes.
  • This study looked at 35 Ewing sarcoma patients to see how DNA repair mechanisms correlate with different clinical features of the disease, focusing on two DNA repair pathways: non-homologous end joining (NHEJ) and homologous recombination (HR).
  • Findings indicate that these repair pathways are disrupted in Ewing sarcoma, and low levels of the XRCC4 gene are linked to better survival, suggesting potential new targets for therapy.
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Background: There is lack of sufficient research evidence when we examine how knee osteoarthritis (OA) affects performance of stand to sit, a very important task for daily function.

Aim: The aim of this study was to investigate if women with unilateral knee OA perform the stand to sit task in the same way as healthy adults of the same age.

Methods: Fifteen women with knee OA (age 64.

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The present study was designed to compare the effectiveness of exercise programs with Pilates and Latin dance on older adults' static and dynamic balance. Thirty-two older adults were divided into three groups: Pilates group, Dance group, and Control group. Static and dynamic balance was assessed with following tasks: (a) tandem stance, (b) one-leg stance, and (c) periodic sway with and without metronome guidance.

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Article Synopsis
  • Variability in human movement is crucial and has a chaotic nature, which is often overlooked in traditional visual feedback training methods.
  • The study investigated how well young adults could track visual targets of different complexities while swaying in two directions: Anterior-Posterior (AP) and Medio-Lateral (ML).
  • Results showed that participants had better synchronization in both postural sway and gaze with a complex Lorenz attractor target compared to simpler targets, suggesting that tracking complex movements may enhance visuo-motor adaptability and learning.
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Light fingertip touch between partners swaying rhythmically side by side evokes interpersonal synchrony. In non-dancers and dancers swaying to a metronome, we examined the effects of frequency scaling and touch between the partners on both postural (ankle-hip) and inter-personal coordination. In both groups, touch did not interfere with the ankle-hip coordination.

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