Immunotherapy for Breast Cancer: First FDA Approved Regimen.

1 in 8 women will be affected by breast cancer, which is the most diagnosed malignancy among women. Although breast cancer was regarded as "immunologically cold", recent studies demonstrate that immunotherapy can be successful employed in combination regimens for the treatment of triple negative breast cancer, an aggressive type of breast cancer without many treatment options available. In March 2019, the US Food and Drug Administration granted accelerated approval for the first immunotherapy-based regimen comprising atezolizumab in combination with protein-bound paclitaxel for patients with advanced metastatic TNBC, expressing programmed cell death-ligand 1 (PD-L1) and without previous systemic treatment for metastatic disease.

An updated h-index measures both the primary and total scientific output of a researcher.

The growing interest in scientometry stems from ethical concerns related to the proper evaluation of scientific contributions of an author working in a hard science. In the absence of a consensus, institutions may use arbitrary methods for evaluating scientists for employment and promotion. There are several indices in use that attempt to establish the most appropriate and suggestive position of any scientist in the field he/she works in.

Study of heart rate of professional divers in hyperbarism during simulated diving in saturation with different respiratory mixture.

Study of heart rate of professional divers in hyperbarism during simulated diving in saturation with different respiratory mixture. Study of heart rate of professional divers in hyperbarism (5.5 ATA and 20 ATA) during simulated divings and in saturation with different respiratory mixture (nitrox and heliox respectively) show a nonsignificant difference in bradycardia response.