Publications by authors named "G Sims"

Objectives: Media exposure to extreme police violence is an increasingly widespread problem that has negative consequences for the mental health of viewers. Black Americans are disproportionately impacted by police violence and its negative consequences, but little is understood from their own perspectives as media viewers.

Method: The present study uses a hermeneutic phenomenological approach to better understand Black American experiences of witnessing lethal police violence toward Black Americans via social media.

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Current criminology and corrections research is limited in its ability to fully conceptualize and analyze inequities in the legal systems' response to young people, particularly those with multiple marginalized identities. This article presents a novel methodological framework-the Critical Case File (CCF) approach-to advance methodological innovations in criminal and juvenile legal system research. Specifically, the CCF approach leverages the rich multisystem information available within case file data and analyzes it through a critical lens to examine (a) the structural factors (e.

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Older women with HIV face challenges to their quality of life, including neurocognitive decline, early-onset menopause, and chronic health issues. Chief among these concerns is depression, the most common psychiatric comorbidity among people living with HIV, with rates twice as high among women as men. However, tailored interventions among older women living with HIV and depression are lacking.

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Article Synopsis
  • The study evaluates the effectiveness and safety of repotrectinib, a new ROS1 tyrosine kinase inhibitor, in treating advanced solid tumors, focusing on fusion-positive non-small-cell lung cancer (NSCLC) and resistance mutations like G2032R.
  • The phase 2 trial involved patients who had not previously received ROS1 TKIs, showing a 79% response rate among these individuals, with a median response duration of 34.1 months.
  • Common side effects reported included dizziness (58%), dysgeusia (taste changes, 50%), and paresthesia (tingling sensations).
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Background: Epithelial damage, repair and remodelling are critical features of chronic airway diseases including chronic obstructive pulmonary disease (COPD). Interleukin (IL)-33 released from damaged airway epithelia causes inflammation its receptor, serum stimulation-2 (ST2). Oxidation of IL-33 to a non-ST2-binding form (IL-33) is thought to limit its activity.

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