Publications by authors named "G Simonia"

Numerous studies have shown that dialysis may not be as beneficial to elderly, frail patients with chronic kidney failure and multiple comorbidities as comprehensive conservative therapy (CCT) and that dialysis may worsen the quality of life (QOL), increase hospitalization rates, and cause a significant decline in functional status. Several mortality predictors have been proposed to determine which patients would benefit more from CCT or dialysis. We estimated the short-term risk of death in an 81-year-old male patient with kidney failure and highly severe frailty using the REIN score, a dependable risk prediction model proposed by the European Renal Best Practice Group for the prediction of short-term risk mortality.

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Since 1991, there have been significant changes in medical education in Georgia. Key changes include adapting national legislation toward international standards, establishing the National Center for Education Quality Enhancement (NCEQE), which was recognized in 2018 by the World Federation for Medical Education (WFME) as an accrediting agency and opening the Association for Medical Education in Europe (AMEE) International Networking Center in 2019. Undergraduate medical education, regulated by the Ministry of Education, Science and Youth of Georgia, spans six years.

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This investigation differentiates types of essential hypertension in a Georgian population as well as describes endogenous cardiotonic steroids in salt-sensitive and salt-resistant subjects. This case control study included 185 subjects: 94 cases with stage 1 essential hypertension (JNC7) naïve to antihypertensive treatment, and 91 controls. A salt-sensitivity test was used to dichotomize case and control groups into salt-sensitive and salt-resistant subgroups.

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It has been known that salt-sensitivity of blood pressure is defined genetically as well as can be developed secondary to either decreased renal function or by influence of other environmental factors. The aim of the study was to evaluate the possible mechanism for the development of salt-sensitive essential hypertension in the population of Georgia. The Case-Control study included 185 subjects, 94 cases with Essential Hypertension stage I (JNC7) without prior antihypertensive treatment, and 91 controls.

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