Publications by authors named "G Silvestrini"

Article Synopsis
  • * Understanding inherited traits is essential for making decisions regarding allogeneic hematopoietic cell transplants (allo-HCT) and choosing suitable donors.
  • * The case of a 49-year-old woman with JAK2 V617F-positive primary myelofibrosis (PMF) illustrates the significance of genetic findings, including a variant in the SH2B3 gene, in clinical management and genetic counseling for transplant options.
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Background: In May 2023, Romagna, Italy, faced a devastating flood resulting in 16 fatalities, forced displacement of 26,000 citizens, and significant economic losses. Due to potential water contamination, implementing public health strategies became imperative for the Local Health Authority to mitigate the health consequences, analyze the flood's impact on the local population's health, and detect early anomalies requiring timely public health interventions.

Methods: Between June and July 2023, general practitioners who were part of the RespiVirNet surveillance network completed weekly structured forms.

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Acute myeloid leukemia (AML) with inv(16) is typically associated with a favourable prognosis. However, up to 40 % of patients will eventually experience disease relapse. Herein, we dissected the genomic and transcriptomic profile of inv(16) AML to identify potential prognostic markers and therapeutic vulnerabilities.

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Article Synopsis
  • - The study assessed the knowledge and attitudes about sexually transmitted infections (STIs) among healthcare workers at a hospital in Italy, revealing that many overestimate their understanding of the topic.
  • - A questionnaire completed by 140 healthcare workers showed that only one-third could correctly identify STIs and knew the transmission methods, despite most recognizing HIV and the effectiveness of condoms.
  • - The findings suggest a significant gap in STI education, indicating the need for targeted educational programs for healthcare providers to improve their knowledge and ability to educate patients.
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Article Synopsis
  • - The Herpes Zoster (HZ) vaccination is safe and effective, leading to cost savings in healthcare, and is provided for free in Italy to those aged 65 and older, with active and catch-up campaigns aimed at increasing vaccination coverage.
  • - A study assessed vaccination rates in the Romagna Local Health Authority during 2023, revealing an overall uptake of 13.5% among individuals born in 1958, with variations among different centers and lower rates for those born in 1957 who were excluded from catch-up campaigns.
  • - The use of text messages for alerts did not show significant differences in effectiveness among groups, but having relatives with HZ symptoms decreased reliance on these messages, indicating that combining multiple communication
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