Publications by authors named "G Sighinolfi"

Multiple sclerosis (MS) is a progressive demyelinating disease impacting the central nervous system. Conventional Magnetic Resonance Imaging (MRI) techniques (e.g.

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Article Synopsis
  • The study investigates how sulcal morphometry, which looks at the shape and structure of brain folds, can help predict whether patients with mild cognitive impairment (MCI) will progress to Alzheimer's disease (AD).
  • Using MRI scans, researchers analyzed brain data from patients with AD, those with MCI, and healthy controls, particularly focusing on certain sulci (brain grooves).
  • Results showed that changes in the width of specific sulci, especially in the temporo-occipital and frontal regions, were significant indicators for differentiating between patients who would convert to AD and those who would not, along with correlations to cognitive performance.
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Purpose: We aim to propose a visual quantitative score for muscle edema in lower limb MRI to contribute to the diagnosis of idiopathic inflammatory myopathy (IIM).

Material And Methods: We retrospectively evaluated 85 consecutive patients (mean age 57.4 ± 13.

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Evidence shows that LH participates in enhancing transition from the early stage to the antral stage of folliculogenesis. It has been demonstrated that functional LH receptors are expressed, albeit at a very low level and even in smaller follicles, during the phase that was traditionally considered to be gonadotrophin independent, suggesting a role for LH in accelerating the rate of progression of non-growing and primary follicles to the preantral/antral stage. Hypogonadotropic hypogonadism, together with other clinical conditions of pituitary suppression, has been associated with reduced functional ovarian reserve.

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