Publications by authors named "G Shroff"
Article Synopsis
- - BMS-986156 is a new treatment that enhances T-cell activation and, when combined with other therapies like ipilimumab and nivolumab, shows promise in controlling tumors in advanced solid cancers.
- - The study enrolled 50 patients with stage IV cancers resistant to standard treatments, dividing them into three groups receiving varying combinations of BMS-986156, ipilimumab, or nivolumab, with and without stereotactic ablative radiotherapy (SABR).
- - Results indicated that the combination therapies were generally well tolerated, though 44% of patients experienced treatment-related adverse events, with 12% having more severe events, such as increased liver enzyme levels.
Background: Little is known about factors contributing to burnout and intent to leave in cardiologists and other cardiology health care workers.
Methods And Results: The Coping With COVID survey assessed work conditions, burnout, and intent to leave among physicians, nurses, advanced practice providers, and other clinical staff (OCS) from April 2020 to December 2020. Single-item measures assessed work conditions, burnout (emotional exhaustion), and intent to leave.
Radiation recall pneumonitis is an inflammatory reaction of previously radiated lung parenchyma triggered by systemic pharmacological agents (such as chemotherapy and immunotherapy) or vaccination. Patients present with non-specific symptoms such as cough, shortness of breath, or hypoxia soon after the initiation of medication or vaccination. Careful assessment of the patient's history, including the thoracic radiation treatment plan and timing of the initiation of the triggering agent, in conjunction with CT findings, contribute to the diagnosis.
View Article and Find Full Text PDFAims: Despite known short-term mortality risk of immune checkpoint inhibitor (ICI) pneumonitis, its impact on 1-year mortality, long-term pulmonary function, symptom persistence, and radiological resolution remains unclear.
Methods: We retrospectively analyzed 71 nonsmall cell lung cancer (NSCLC) patients treated with anti-PD(L)1 monoclonal antibodies between 2018-2021, who developed pneumonitis. Clinical and demographic covariates were collected from electronic medical record.
Imaging plays a key role in clinical staging of lung cancer and guiding therapy. A thorough understanding of the staging system including the nomenclature and updates is necessary to tailor treatment plans and optimize patient care. The 9th edition of the Tumor, Node, Metastasis staging system for lung cancer has no changes for T classification and subdivides N2 and M1c categories.
View Article and Find Full Text PDF