Publications by authors named "G Shayo"

Silver nanoparticles (SNPs) are a type of nanomaterial with wide applications in water treatment, medicine, food packaging, and industrial processes. Their unique optical, electrical, thermal conductivity, and biological properties distinguish them from other metal ions and liken them to noble metals like gold and copper. The present review explores the diverse applications, preparation techniques, mechanism of action of SNPs, and properties of SNPs focusing on their bactericidal activities and potential impacts on human health.

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  • Foreign body aspiration in adults is rare and can be challenging to diagnose, often resulting in delayed treatment.
  • Chronic aspiration can lead to serious complications like bronchiectasis, atelectasis, and lung fibrosis.
  • The case study highlights a primary school teacher who was diagnosed with foreign body aspiration 11 years after it occurred, having received unnecessary antibiotics and antituberculous therapy due to the delay.
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  • A middle-aged woman experienced chronic foot arthritis that led to a non-healing ulcer, which didn't respond to standard treatments.
  • After developing neurological issues, she was treated with antitubercular medications that healed the ulcer but caused other serious complications, including cerebral tuberculoma and tuberculous meningitis.
  • Despite efforts for diagnosis and treatment, she ultimately died from the complications and a likely hospital-acquired infection, underscoring the difficulties in identifying rare disease presentations in endemic regions.
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The study explores barriers and suggestions for improving viral load testing (VLT) uptake in Tanzania, revealing that only 58% of patients receive VLT annually, contrary to the Tanzanian National Guidelines toward the 95-95-95 UNAIDS targets. Twelve individual interviews and three patient-focus groups were conducted as part of a qualitative study conducted in six human immunodeficiency virus (HIV) clinics in Dar es Salaam to identify potential suggestions for access enhancement, as well as barriers to VLT uptake. Using King's theory of goal attainment, we found that missing appointments was the primary individual barrier to VLT uptake, along with limited knowledge among individuals living with HIV.

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Aims: Methadone maintenance therapy (MMT) exhibits significant variability in pharmacokinetics and clinical response, partly due to genetic variations. However, data from sub-Saharan African populations are lacking. We examined plasma methadone variability and pharmacogenetic influences among opioid-addicted Tanzanian patients.

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