Publications by authors named "G Sharpe"
Article Synopsis
- The study aims to see if changes in macular perfusion density (PD) can be detected through OCTA imaging before the thinning of the ganglion cell layer (GCL) in patients with early glaucoma.
- Researchers compared OCT and OCTA imaging in 80 glaucoma patients and 42 healthy subjects every 4 months, assessing GCL thickness and macular PD in different areas of the retina.
- Results indicated that a decrease in GCL thickness often occurs before noticeable changes in macular PD, suggesting that tracking GCL thickness may be more effective in identifying early glaucoma progression.
Introduction: Dyspnoea perception is influenced by a complex interplay of physiological, psychological, and environmental factors. Recently, we showed that males with high trait self-control experience less dyspnoea and persist for longer in a carbon dioxide (CO) rebreathing challenge than males with low trait self-control. As self-control can also vary within individuals (state self-control), the primary aim of the present study was to investigate whether prior self-control exertion influenced perceptions of dyspnoea and tolerance of a CO rebreathing challenge in healthy young males.
View Article and Find Full Text PDFObjective: To compare the agreement and repeatability of intraocular pressure (IOP) measured with the slit lamp-mounted ST500 rebound tonometer (iCare Finland Oy), the hand-held IC200 rebound tonometer (iCare Finland Oy), and Goldmann applanation tonometry (GAT).
Design: Cross-sectional study.
Participants: Glaucoma patients and staff of the Eye Care Centre, Nova Scotia Health.
Article Synopsis
- The study aims to evaluate how effectively the thickness of different macular retinal layers can differentiate glaucomatous eyes and glaucoma suspects from healthy eyes using optical coherence tomography (OCT).
- The findings reveal that the nerve fiber layer (NFL) and ganglion cell layer (GCL) have the best diagnostic accuracy, with the ganglion cell complex (GCC) performing similarly, while the inner plexiform layer (IPL) is less effective. The combination of NFL or GCL yields the highest sensitivity and overall diagnostic performance.
- The results underscore the necessity of assessing individual retinal layers rather than relying solely on combined metrics, as the best-performing layers can vary based on the specific area of the retina
Purpose: To assess the impact of working distance (WD) on optical distortion in optical coherence tomography (OCT) imaging and to evaluate the effectiveness of optical distortion correction in achieving consistent retinal Bruch's membrane (BM) layer curvature, regardless of variations in WD.
Methods: Ten subjects underwent OCT imaging with four serial macular volume scans, each employing distinct WD settings adjusted by balancing the sample and reference arm of the OCT interferometer (eye length settings changed). Either of two types of 30° standard objectives (SOs) was used.