In vivo NMR is evolving into an important tool to understand biological processes and environmental responses. Current approaches use flow systems to sustain the organisms with oxygenated water and food (e.g.
View Article and Find Full Text PDFBackground: Many cancer survivors following primary treatment have prolonged poor quality of life.
Aim: To determine the effectiveness of a bespoke digital intervention to support cancer survivors.
Design And Setting: This was a pragmatic parallel open randomised trial in UK general practices (ISRCTN:96374224).
Background: Increasing healthy behaviours (e.g. physical activity) can improve cancer survivors' quality of life.
View Article and Find Full Text PDFAmyloid β oligomers (Aβo) are the main toxic species in Alzheimer's disease, which have been targeted for single drug treatment with very little success. In this work we report a new approach for identifying functional Aβo binding compounds. A tailored library of 971 fluorine containing compounds was selected by a computational method, developed to generate molecular diversity.
View Article and Find Full Text PDFAn amendment to this paper has been published and can be accessed via a link at the top of the paper.
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