WHO study on Prevention of REcurrences of Myocardial Infarction and StrokE (WHO-PREMISE).

Objective: To determine the extent of secondary prevention of coronary heart disease (CHD) and cerebrovascular disease (CVD) in low- and middle-income countries.

Methods: A descriptive cross-sectional survey of a sample of 10 000 CHD (85.2%) and CVD (14.

The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men.

Light to moderate drinking is associated with lower risk of coronary heart (CHD) than non-drinkers. We have examined the relationships between total alcohol intake and type of alcoholic beverage and several potential biological mechanisms. We carried out the study in 3158 men aged 60-79 years drawn from general practices in 24 British towns with no history of myocardial infarction, stroke or diabetes and who were not on warfarin.

Influence of fathers' social class on cardiovascular disease in middle-aged men.

Background: The independent effect of early life circumstances on adult cardiovascular risk is still unresolved. We assessed the associations of father's social class with cardiovascular risk factors and with risk of ischaemic heart disease and stroke in adult life.

Methods: We did a longitudinal study of cardiovascular disease in 5934 men aged 40-59 years at enrollment.

Hypercholesterolaemia and a silent MI.

Results of investigations in extraordinary patients should be dealt with cautiously; it is often prudent to repeat tests. Though the aims of treatment in such cases are often the same, differences in approach to the problem are illuminating.