[The induction of tolerance in mice for a human melanoma graft].

Mouse skin allografts and intramuscular BRO human melanoma xenografts were successfully established in phenotypically normal mice after inducing immunological tolerance in the recipients. Tolerance was achieved by inoculating allogenic embryonic liver cells after the whole-body irradiation. No immunological rejection was evident in BRO xenografts for 34 days after transplantation.

[Modeling of the "universal" bone marrow using monoclonal antibodies].

The data on the application of monoclonal antibodies (ICO-10) and rabbit complement for working the conditions of allogeneic bone marrow transplantation are presented in the paper. The treatment with monoclonal antibodies and bone marrow complement from BALB/c mice for 2 times prevented the development of transplant versus host reaction and completely protected lethally irradiated (CBA X X C57B1/6)FI mice-recipients from death. Thymus atrophy and the absence of T-cells in the peripheral blood was observed in these mice.

[Inhibition of the growth of the Ca-755 tumor in mice with reconstitution of hematopoiesis].

Data on the growth inhibition of Ca-755 tumor transplanted to mice two months after hemopoiesis recovery with syngeneic bone marrow cells or allogeneic fetal liver are presented.

[The effect of Trichinella spiralis on the susceptibility and antibody production to vaccinia virus].

Trichinella spiralis exerts an immunodepressive effect on production of antihemagglutinins to vaccinia virus in mice, increases the susceptibility to the virus in mice and rabbits. Deaths of mice inoculated with vaccine virus and generalization of the vaccination process in rabbits were observed at 33 days of invasion.